GANLÖV, Karin,ÖSTBERG, Magnus,LINDBERG, Per L.,SUNDÉN, Gunnel E.,GUSTAVSSON, Bengt
申请号:
AU2019205861
公开号:
AU2019205861A1
申请日:
2019.01.04
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention provides methods for treating patients diagnosed with colorectal cancer and metastatic colorectal cancers in a chemotherapeutic regimen comprising the administration of [6R]-5,10-methylene tetrahydrofolate (6R-MTHF), 5-fluorouracil (5-FU), bevacizumab, and oxaliplatin. The methods reduce disease progression and provide improved overall response rates compared to standard treatments with other folates such as folinic acid.