The present invention relates to a Lactobacillus-fermented solution having weight control effects and obesity prevention effects, and a fermented beverage to which the Lactobacillus-fermented solution is used as a raw material. More specifically, the present invention relates to a Lactobacillus-fermented solution and a fermented beverage to which the Lactobacillus-fermented solution is used as a raw material. To this end, the Lactobacillus-fermented solution is prepared by the following steps: drying bread produced by using probiotics, and then grinding the same to obtain bread powder; adjusting sugar content by adding purified water and saccharides; and adding a culture solution of Lactobacillus sp. nhs221 strain (Accession No. KCTC-11749BP), and then carrying out fermentation and aging.본 발명은 비만 예방 및 체중 조절 효과를 지닌 유산균 발효액 및 이를 원료로 사용한 발효 음료에 관한 것이다. 더욱 상세하게는 생균제제로 제조된 빵을 건조시킨 후 분쇄시켜 수득된 빵 분말에 정제수 및 당류를 넣고 당도를 조절시킨 후 락토바실러스속 nhs221 균주(기탁번호 KCTC-11749BP호) 배양액을 넣어 발효 숙성시킨 유산균 발효액 및 이를 원료로 사용한 발효 음료에 관한 것이다.