This application involves imidazolone compounds, its pharmaceutically acceptable salt, solvate, polymorph or prodrug, further relates to the pharmaceutical composition comprising above-mentioned substance and prevent and treat the purposes of the diseases related such as cancer of protein kinase, metabolic disease, cardiovascular disease with what.本申請涉及咪唑酮類化合物、其藥學可接受的鹽、溶劑化物、多晶形物或前藥，還涉及包含上述物質的藥物組合物和用於預防和治療蛋白激酶相關性疾病如癌症、代謝疾病、心血管疾病等的用途。
