Wanhui Liu;Jun Li;Youxin Li;Aiping Wang;Kaoxiang Sun;Lifang Sun
发明人:
Youxin Li,Aiping Wang,Wanhui Liu,Kaoxiang Sun,Jun Li,Lifang Sun
申请号：
US13989550
公开号：
US20130309314A1
申请日:
2011.11.25
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The disclosure provides a composition comprising rotigotine or a pharmaceutically acceptable salt thereof； at least one poly(lactide-co-glycolide) (PLGA)； and at least one fatty acid, wherein the at least one fatty acid is at least 0.5% in weight relative to the total weight of the composition. The composition as disclosed herein has significantly reduced burse release effect. The disclosure also provides a method of treating Parkinson's disease comprising administering an effective amount of the composition as disclosed to a subject in need thereof.
