The disclosure relates to a composition comprising rotigotine or a pharmaceutically acceptable salt thereof； at least one poly(lactide-co-glycolide) (PLGA)； and at least one fatty acid, wherein the at least one fatty acid is at least 0.5% in weight relative to the total weight of the composition. The composition as disclosed herein has significantly reduced burse release effect. The disclosure also provides a method of treating Parkinson's disease comprising administering an effective amount of the composition as disclosed to a subject in need thereof.
