Susan A. McDowell,Robert E. Sammelson,Larry A. Sklar,Mark K. Haynes
申请号:
US13773871
公开号:
US09259415B2
申请日:
2013.02.22
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure relates to molecules which function as selective modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases and, in particular, CDC42 GTPase, and their use to treat bacterial infection including systemic infection from sources such as Staphylococcus aureus.