Chong Kun Dang Pharmaceutical Corp.;CHONG KUN DANG PHARMACEUTICAL CORP
发明人:
申请号:
EP14869323.7
公开号:
EP3080125B1
申请日:
2014.12.12
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.