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NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES
专利权人:
Katholieke Universiteit Leuven
发明人:
Graciela Andrei,Steven De Jonghe,Elisabetta Groaz,Piet Herdewijn,Min Luo,Dominique Schols,Robert Snoeck
申请号:
US16495606
公开号:
US20200016180A1
申请日:
2018.03.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to novel phosphonoamidate prodrugs. The invention also relates to the use of these novel phosphonate-modified nucleosides to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses such as the herpes simplex virus 1, herpes simplex virus 2, human cytomegalovirus, varicella zoster virus, vaccinia virus and adenovirus.
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