Shanghai Institute of Materia Medica; Chinese Academy of Sciences
发明人:
申请号：
EP13825341.4
公开号：
EP2881395A1
申请日:
2013.07.24
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Provided is a piperazinotriazole compound represented by general formula I or an isomer, a pharmaceutically acceptable salt, ester, prodrug or hydrate thereof. Also provided are a method for preparing the compound, a drug composition containing the compound, and a use thereof as a high-selectivity poly(ADP-ribose)polymerase-1 (PARP 1) inhibitor in the preparation of drugs for the prevention and / or treatment of PARP-related diseases.
