A system configured to heat items to a temperature sufficient to kill bed bugs includes an enclosure and a hydronic heating system. The hydronic heating system is capable of heating the interior of the enclosure to at least approximately 110° F. The hydronic heating system includes a heater that heats a liquid. The liquid is used to transfer heat into the interior of the enclosure. In one embodiment, the hydronic heating system includes a hydronic radiant heating system and a hydronic forced air heating system. The enclosure can be used to kill bed bugs by positioning an item that includes bed bugs in the enclosure and heating the interior of the enclosure to a temperature and for a duration that is sufficient to kill the bed bugs.
