PROCÉDÉ ET SUBSTANCE THÉRAPEUTIQUE POUR LE TRAITEMENT ET LA RÉGULATION DE LA FORMATION DE LA MÉMOIRE

• 收藏
• 分享

专利权人:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人:

WOOD, MARCELO, ANDRES

申请号：

EP11813208

公开号：

EP2598133A4

申请日:

2011.07.28

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

A methodology and pharmaceutical and gene therapies for the treatment and regulation of memory function are provided. The invention identifies specific HDAC, and in particular, HDAC3 and HDAC4 as negative regulators of memory formation and specifically targets one or both HDAC3 and HDAC4 for down-regulation. By specifically targeting HDAC3 and HDAC4 with small molecule inhibitors and gene therapies it is possible to provide a powerful therapeutic approach to facilitate gene expression during memory formation that can lead to the regulation and treatment of memory disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/