The present invention relates to the use of antrodia camphorata in the treatment of skin conditions, allergic rhinitis, diabetes mellitus and its complications, cancer cachexia, hypercholesterolemia, gout in a subject in need of such treatment. The present invention is also directed to the use of antrodia camphorata in the prevention and treatment of oral cancer and arterial restenosis, in a subject in need of such prevention. The methods comprise the steps of: identifying a subject in need thereof, and administering to the subject a formulation comprising an effective amount of antrodia camphorata, whereby the symptoms in the subject are reduced or prevented. The composition can be a pharmaceutical composition or a nutraceutical composition.本發明揭示牛樟芝用於治療需要治療之個體的皮膚疾病、過敏性鼻炎、糖尿病和其併發症、癌症惡病質、高膽固醇血症、痛風的方法。本發明還提供牛樟芝用於預防和治療需要該預防和治療個體之口腔癌和動脈再狹窄的方法。該方法包含以下步驟:識別有需要的個體;向該個體投與有效量之牛樟芝的制劑,由此減輕或預防該個體的症狀。該組合物可以是醫藥組合物或營養性組合物。