Olaf PANKNIN,Ingo HARTUNG,Hartmut REHWINKEL,Duy NGUYEN,Ludwig ZORN,Petra HELFRICH,Katja ZIMMERMANN,Roland NEUHAUS
申请号：
US15746352
公开号：
US20180215717A1
申请日:
2016.07.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to compounds of general formula (I): in which R1, R2, R3, R4, R6, R7, R8, R9, R10, R11, R12, R13 and X are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
