Sven RING,Olaf PANKNIN,Katja ZIMMERMANN,Judith GÜNTHER,Lars BÄRFACKER
申请号:
US15580372
公开号:
US20180170882A1
申请日:
2016.06.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to benzimidazol-2-amines of general formula (I), in which R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.