AND AFFITECH RESEARCH AS; INC.;PEREGRINE PHARMACEUTICALS;PEREGRINE PHARMACEUTICALS, INC.
发明人:
KAVLIE, ANITA,SCHLUNEGGER, KYLE
申请号:
NZ58605308
公开号:
NZ586053A
申请日:
2008.11.07
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Provided is an isolated antibody that binds to VEGF and that comprises at least one heavy chain variable region that comprises three CDRs with defined sequences or their variants containing conservative amino acid substitutions. The antibodies can be used to treat various diseases including cancer, arthritis and psoriasis, by inhibiting angiogenesis or lymphangiogenesis.