PHARMACEUTICAL COMPOSITION MADE OF MICROPARTICLES FOR THE SLOW RELEASE OF AN ACTIVE SUBSTANCE AT LEAST DURING A PERIOD COVERING THE 6TH MONTH AFTER INJECTION OF SAID COMPOSITION, SAID COMPOSITION COMPRISING A GROUP OF MICROPARTICLES MADE OF A COPOLYMER OF THE PLGA TYPE WHICH INCORPORATE AN ACTIVE SUBSTANCE IN THE FORM OF A WATER INSOLUBLE PEPTIDE SALT； SAID COPOLYMER FURTHERMORE COMPRISING AT LEAST 75 % OF LACTIC ACID AND AN INHERENT VISCOSITY BETWEEN 0.1 AND 0.9 DL/G, AS MEASURED IN CHLOROFORM AT 25 OC AND AT A POLYMER CONCENTRATION OF 0.5 G/DL； SAID MICROPARTICLES FURTHERMORE HAVING A SIZE DISTRIBUTION DEFINED AS FOLLOWS : - D (V,0.1) IS BETWEEN 10 AND 30 MICROMETERS, -D (V,0.5) IS BETWEEN 30 AND 70 MICROMETERS, - D(V,0.9) IS BETWEEN 50 AND 1 10 MICROMETERS. FIGURE 3
