A cosmetic and / or pharmaceutical preparations prepared, or peptide fragment and / or a peptide fragment of parathyroid hormone according to the cosmetics, the following structures in view from the essential or non-essential skin deterioration to prevent the skin and human hair of the treatment, and the appearance worsened it is proposed to use a derivative and / or salt:R1-NH-AA-R2[In the formula,R1 is -H, or -OH, -SH, -COOH groups of which may be functionalized or -CONH 2, from 1 to 24 carbon atoms, a linear saturated or unsaturated acyl group or a branched saturated or unsaturated acyl groups, or two or acids such as It is selected from the group formed sterol group is coupled with the peptide by a functional groupR2 = -OH, or is C 1 -C 24 linear or branched saturated or unsaturated alkyl groups functionalized with OH groups branched saturated or unsaturated alkyl group, or a group of sterolAA is completely or partially corresponding to the sequence of amino acid according to SEQ ID NO: 1 which corresponds to PTH (28 to 34) region. Addition to, a cosmetic preparation containing the derivative of a peptide fragment of parathyroid hormone according to the following structure is proposed:R1-NH-AA-R2[In the formula,R1 is -H, or -OH, -SH, -COOH groups of which may be functionalized or -CONH 2, from 1 to 24 carbon atoms, a linear saturated or unsaturated acyl group or a branched saturated or unsaturated acyl groups, or two or acids such as It is selected from the group formed sterol group is coupled with the peptide by a functional groupR2 = -OH, or is C 1 -C 24 linear or branched saturated or unsaturated alkyl groups functionalized with OH groups branched saturated or unsaturated alkyl group, or a group of sterolAA is completely or partially corresponding to the sequence of amino acid according to PTH (28 to 34) domain of SEQ ID NO: 1However, when R2 is the, or R2 corresponds to OH only if different from -OH, the R1 is only H, R1 is different from H].화장품 및/또는 약제학적 제
