SITE-DIRECTED MODIFICATION OF FACTOR IX

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专利权人:

BAYER HEALTHCARE LLC

发明人:

BROOKS, ALAN, R.,MURPHY, JOHN, E.,SETO, MARIAN,JIANG, XIAOQIAO,KIEWLICH, DAVID,PATEL, CHANDRA

申请号：

EP09747101

公开号：

EP2282767A4

申请日:

2009.04.15

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The invention relates to modified Factor IX polypeptides such as Factor IX polypeptides with one or more introduced cysteine sites. The modified Factor IX polypeptides may be conjugated to a biocompatible polymer. The invention also relates to methods of making modified Factor IX polypeptides, and methods of using modified Factor IX polypeptides, for example, to treat patients afflicted with hemophilia B.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/