An air assisted lateral patient transport system that uses a semi-permeable fabric with a uniform air permeable surface on the bottom layer of the plenum. The semi-permeable fabric provides lift to assist moving patients, and allows cleaning solutions to enter the device for cleaning. The patient transfer device allows independent control of air pressure in each air chamber such that air pressure can be dynamically modified to avoid bed sores and other blood circulation related problems during transport. In addition, a unique patient restraint strap is employed that eliminates buckles for patient safety and comfort. The multi chambered patient transport system 1 provides a support surface on which to receive a patient, easily move the patient, and provide air pressure controls to avoid bed sores during transport and while being treated at a medical facility. The system includes a plurality of independent air chambers to independently control air pressure in each air chamber.