Y. Joseph MO;Xudong YUAN;NAL PHARMACEUTICAL GROUP LIMITED
发明人:
Y. Joseph MO,Xudong YUAN
申请号：
US16641522
公开号：
US20200230068A1
申请日:
2018.08.08
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Nanoparticles and microspheres are provided for delivering an anticancer agent or other active agents to a subject. The nanoparticles and the microspheres are formed from a core that is encased by a coating or shell that includes a somatostatin-albumin fusion protein or analogue thereof. The somatostatin-albumin fusion protein includes at least one albumin (or an analog thereof) moiety, at least one somatostatin moiety (e.g. SST-14, SST-28), and at least one spacer connecting albumin to albumin, somatostatin to somatostatin and/or albumin to somatostatin moieties.
