BLASS, BENJAMIN ERIC,ABOU-GHARBIA, MAGID A.,CHILDERS, WAYNE E.,IYER, PRAVIN,BORUWA, JOSHODEEP,BOBBALA, RAMREDDY,NIMMAREDDY, RAJASHEKAR REDDY
申请号:
CA2925294
公开号:
CA2925294A1
申请日:
2014.09.25
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Pharmaceutical compositions described in this document comprise 5-(phenoxymethyl)-1,3-dioxane analogs having a disease-modifying action in the treatment of diseases associated with the production of cortisol that include metabolic syndrome, obesity, headache, depression, hypertension, diabetes mellitus, Cushing's Syndrome, pseudo-Cushing syndrome, cognitive impairment, dementia, heart failure, renal failure, psoriasis, glaucoma, cardiovascular disease, cancer, stroke, incidentalomas, or any diseases involving the overproduction of cortisol.