BLASS, BENJAMIN ERIC,ABOUGHARBIA, MAGID A.,CHILDERS, WAYNE E.,IYER, PRAVIN,BORUWA, JOSHODEEP
申请号：
CA2924168
公开号：
CA2924168A1
申请日:
2014.09.15
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Embodiments of the present invention relate to novel cytochrome P450 inhibitors and pharmaceutical compositions thereof having a disease-modifying action in the treatment of diseases associated with the production of cortisol that include metabolic syndrome, obesity, headache, depression, hypertension, diabetes mellitus, Cushing's Syndrome, pseudo-Cushing syndrome, cognitive impairment, dementia, heart failure, renal failure, psoriasis, glaucoma, cardiovascular disease, cancer, stroke or incidentalomas.
