THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
发明人:
GIBSON, IAIN RONALD,SKAKLE, JANET MABEL SCOTT,CONWAY, JORDAN CHRISTOPHER,ANNAZ, BASIL
申请号：
CA2803226
公开号：
CA2803226C
申请日:
2011.06.22
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The bone graft system comprises a solid inorganic component, which is bone graft material, and a hydrogel. The hydrogel contains >；2ppm of silicon ions, calculated as parts by weight of Si per million of the aqueous component of the hydrogel. Preferably, the solid inorganic component comprises hydroxyapatite or a silicon-containing hydroxyapatite, and may be a silicon- containing hydroxyapatite having a Ca/P ratio in the range 2.05 to 2.55 and a Ca/(P + Si) molar ratio less than 1.66. Bone healing is promoted by delivery of silicon ion release from the hydrogel and by the solid inorganic component stimulating cell behaviour.
