This invention concerns a hydrogen peroxide sterilization device, with injection of hydrogen peroxide vapor, provided with a vaporizer that feeds a sterilization chamber, with a dose that varies in function of the control performed by a computer or control unit. The vaporizer works with a pressure inferior to the atmospheric one and is heated by an electrical resistance heater, or by micro-waves. All the vaporization process is made in vacuum, by heat or ultra-sounds. The filling of the sterilant agent is made drop-by-drop by a capillary tube which transforms the liquid into a pulverized gas. The computer controls the electrical valve following the dosing pump from the pressure and/or temperature information that comes from various pressure and/or temperature sensors, whereby the pressure inside the chamber is maintained during the sterilization process in a constant predefined value, appropriate to use simple cellulose-base paper or paper composed to the packaging of the devices. The invention also refers to the hydrogen peroxide sterilization process that uses the referred device. The present invention is also appropriate to sterilize cork stoppers and stomatology material in chambers of reduced size, or other suitable materials for sterilization in bigger chambers. Based on the invention it is possible to create the REGISTOMETER FOR EVALUATING BIOLOGICAL INDICATORS AND CHEMICAL INDICATORS for laboratory studies of biological death and color change of chemical indicators, with hydrogen peroxide as sterilization agent.