AN IMPROVED PROCESS FOR PREPARATION OF FENSPIRIDE

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专利权人:

发明人:

GURJAR MUKUND KESHAV,MAIKAP GOLAKCHANDRA SUDARSHAN,MAHAJAN ULHAS SUPADU,SHINDE SOPAN NARAYAN,PATIL DEVIDAS BARKU,MEHTA SAMIT SATISH

申请号：

IN1554/MUM/2011

公开号：

IN2011MU01554A

申请日:

2011.05.23

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

The present invention provides a novel process for preparation of Fenspiride. The process comprises reaction of N-(2-phenyiethyl)-2-oxo-6-azaspiro[2.5]octane with alkali cyanate such as potassium cyanate to give Fenspiride (I), which on subsequent treatment with hydrogen chloride in presence of methyl isobutyl ketone as solvent provides Fenspiride hydrochloride of formula (la) of desired purity.

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中国工程科技知识中心

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