The invention relates to compounds of formulawherein Ris hydrogen, halogen, cyano, lower alkyl, lower alkyl substituted by halogen, lower alkoxy, lower alkoxy substituted by halogen or C(O)NH, or is phenyl optionally substituted by halogen, cyano or lower alkoxy substituted by halogen, or is 2,2-difluorobenzo[d][1,3]dioxol-5-yl, or is 6-(trifluoromethyl)pyrazin-2-yl or 5-(trifluoromethyl)pyrazin-2-yl or is 6-(trifluoromethyl)pyrimidin-4-yl, or is 6-(trifluoromethyl)pyridin-3-yl, or is 5-cyanopyrazin-2-yl or is 2-(trifluoromethyl)pyrimidin-4-yl n is 1 or 2 Ris halogen, lower alkyl or cyano and Ris hydrogen, or Ris hydrogen and Ris halogen, lower alkyl or cyano X is a bond, -NR-, -CHNH- or -CHR- R is hydrogen or lower alkyl Z is a bond, -CH- or -O- Ar is phenyl or is heteroaryl, selected from the group consisting of 1H-indazole-3-yl, pyridine-2-yl, pyridine-3-yl, pyridine-4-yl, pyrimidine-5-yl, 1H-pyrazole-3-yl, 1H-pyrazole-4-yl or 1H-pyrazole-5-yl or to pharmaceutically suitable acid addition salts thereof, which may be used for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinsons disease, neurodegenerative disorders, Alzheimers disease, epilepsy, migraine, hypertension, substance abuse, metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.Изобретение относится к соединениям формулыгде Rпредставляет собой водород, галоген, цианогруппу, низший алкил, низший алкил, замещенный галогеном, низшую алкоксигруппу, низшую алкоксигруппу, замещенную галогеном или C(O)NH, или представляет собой фенил, возможно, содержащий в качестве заместителя галоген, цианогруппу или низшую алкоксигруппу, замещенную гало
