The present invention relates to a pharmaceutical composition that enables easy control of a release pattern of galantamine or pharmaceutically acceptable salts thereof as an active ingredient. The pharmaceutical composition in the form of matrix comprises: granules including a therapeutically effective amount of galantamine or pharmaceutically acceptable salts thereof and aminoalkyl methacrylate copolymer; and ethylcellulose polymer particles having average particle diameter of 1 to 450 µm, wherein the amount of the galantamine is 8n mg and the average particle diameter of the ethylcellulose polymer particles is more than 15(n- 1)3 µm and not more than 15n3 µm.