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נגזרות 2–אוקסו–3–בנזיל–בנזוקסאזול–2–אחד ותרכובות קשורות כמעכבי met קינאז לטיפול בגידולים, תרופות המכילות אותן ושימושיהן
专利权人:
MERCK PATENT GMBH
发明人:
申请号:
IL20250509
公开号:
IL202505A
申请日:
2009.12.03
申请国别(地区):
IL
年份:
2014
代理人:
摘要:
Described are compounds which inhibit, regulate and/or modulate kinase signal transduction, for example of Met kinase. The compounds are of the formulae A1 to A148 and B1 described herein, including 2-oxobenzoxazol-3-ylmethyl]phenyl}carbamate and 2-oxooxazolo[4,5-b]pyridin-3-ylmethyl)phenyl]carbamate compounds, and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. Also described are compositions containing these compounds. Also described are methods for the treatment of diseases in which the inhibition, regulation and/or modulation of kinase signal transduction plays a role by administering these compounds.
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中国工程科技知识中心
来源网址:
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