Stable injectable diclofenac compositions

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专利权人:

Shimoda Biotech (Pty) Ltd

发明人:

Penkler, Lawrence John

申请号：

AU2011221386

公开号：

AU2011221386B2

申请日:

2011.09.07

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2011221386B220130207.pdf#####Abstract This invention relates to stable parenteral aqueous solutions comprising either (a) diclofenac or a pharmaceutically acceptable diclofenac salt and a cyclodextrin, or (b) an inclusion complex of diclofenac or a pharmaceutically acceptable diclofenac salt and a cyclodextrin, or a mixture of (a) and (b), which are suitable for intramuscular and intravenous administration. The solutions contain diclofenac or diclofenac salt, cyclodextrin, and an antioxidant selected from monothioglycerol, or a combination of ethylene diamine tetra-acetic and N-acetylcysteine.

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