KUMAR, KUNAL,WANG, PENG,SANCHEZ, ROBERTO,OCANA, ADOLFO GARCIA,STEWART, ANDREW,DEVITA, ROBERT
申请号:
CA3093340
公开号:
CA3093340A1
申请日:
2019.03.20
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Described herein are compounds having the following structure: formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof. Also disclosed are compositions containing the compounds, methods of inhibiting activity of DYRKl A in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder.