The invention provides for a transdermal drug delivery device for forming adrug delivery patch system comprising: a) an actuator (100) comprising: i) anouter body defining a top of the actuator, the outer body containing a cavity；ii) a controller board comprising driving electronics and a battery, thecontroller board being positioned within the cavity； and iii) an interfaceconnection port for receiving a porator array, the interface connection portcontaining an anode and a cathode； b) a reservoir patach attached to the anextention tub, the reservoir patch being applied to the microporated area of atissue membrane after poration.
