Lianyun Zhao,Duan Liu,Shuyi Tang,Amit K. Mandal,Umar Faruk Mansoor,Lalanthi Dilrukshi Vitharana,Panduranga Adulla P. Reddy,M. Arshad Siddiqui
申请号：
US13818177
公开号：
US08883801B2
申请日:
2011.08.22
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to certain pyrazolo[1,5-a]pyrimidine compounds of Formula (I)as inhibitors of mammalian Target Of Rapamycin (mTOR) kinase, which is also known as FRAP, RAFT, RAPT or SEP. The compounds may be used in the treatment of cancer and other disorders where mTOR is deregulated. The present invention further provides pharmaceutical compositions comprising the pyrazolo[1,5-a]pyrimidine compounds.
