Methods and systems relating to an ankle and foot support system are disclosed. In some embodiments, a covering having a cable tightening mechanism may be associated with a cable that is slidably engaged with the cover. In some embodiments, the cable may be slidably engaged with a tube guide that is attached to the cover. In some embodiments, the cable may form an exposed loop that associates with a loop receiving member. In some embodiments, the loop receiving member may be attached to the cover.