Luijkx, Dionisius Marinus Antonius Maria,Koppelman, Stefan Johan,Sleijster-Selis, Henriette Emilie,Van Den Hout, Robertus Henricus Joannes Alfonsus
申请号：
AU2009265601
公开号：
AU2009265601B2
申请日:
2009.07.06
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention relates to pharmaceutical compositions for immunotherapy, for example for immunotherapy of peanut allergy. Further, the present invention relates to methods for the preparation of the present pharmaceutical compositions for immunotherapy, and their use in immunotherapy. Furthermore, the present invention relates to processes for modifying allergens thereby enhancing their application in immunotherapy. The invention also relates to the present modified allergens and pharmaceutical compositions comprising the present allergens, as well as to the use thereof in immunotherapy. According to a particularly preferred embodiment, the present invention relates to pharmaceutical compositions for immunotherapy comprising reduced and alkylated naturally occurring peanut allergens Ara h2 and/or Ara h6, or derivates or isoforms thereof wherein said pharmaceutical composition substantially does not comprise Ara h1 and/or Ara h3.
