Stefan Johan KOPPELMAN,Robertus Henricus Joannes Alfonsus VAN DEN HOUT,Henriette Emilie SLEIJSTER-SELIS,Dionisius Marinus Antonius Maria LUIJKX
申请号：
US14637198
公开号：
US20150273052A1
申请日:
2015.03.03
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to pharmaceutical compositions for immunotherapy, for example for immunotherapy of peanut allergy. Further, the present invention relates to methods for the preparation of the present pharmaceutical compositions for immunotherapy, and their use in immunotherapy.Furthermore, the present invention relates to processes for modifying allergens thereby enhancing their application in immunotherapy. The invention also relates to the present modified allergens and pharmaceutical compositions comprising the present allergens, as well as to the use thereof in immunotherapy.According to a particularly preferred embodiment, the present invention relates to pharmaceutical compositions for immunotherapy comprising reduced and alkylated naturally occurring peanut allergens Ara h2 and/or Ara h6, or derivates or isoforms thereof wherein said pharmaceutical composition substantially does not comprise Ara h1 and/or Ara h3.
