1 i z, as k i valid values of , invalid value or missing including the value. Here, the time t i signal s in i , the physical, chemical, biological, environmental and / or technical acquired by technical setup including the data. In this way, providing a set of data points, each smoothed data point (t k , s k ) for, generating a smoothed set. Each smoothed data point (t k , s k ) for, until smooth set is verified to contain data points of the minimum number, a large gap to remove the tracking data generated from. Next, the smoothed data point (t k , s k ) for, calculates a first slope set, at least one exponential smoothing thereto apply, thereby, determines the inclination set that has been modified at least once. By integrating the inclination set that has been modified at least once, smoothed data point (t k , s k ) value for is determined, returned It is. The method, without introducing lag, with minimum distortion, providing excellent smoothing simultaneously, it is possible to report the derivative of the set of smoothed data points. This method is particularly suitable for real time or near real-time measurements that may contain large gaps in the data point streamsFIELD 11≦i≦z、k