NANYANG TECHNOLOGICAL UNIVERSITY;NATIONAL UNIVERSITY OF SINGAPORE
发明人:
GRUBER, GERHARD,BATES, RODERICK WAYLAND,HOTRA, ADAM,DICK, THOMAS,PETHE, KEVIN
申请号:
CA3056590
公开号:
CA3056590A1
申请日:
2018.02.15
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to pyrimidine compounds and compositions for treating tuberculosis. These compounds may be used to target the F1 domain of F-ATP synthase and may be used with bedaquiline or 6-chloro-2-ethyl-N-[[4-[4- [4-(trifluoromethoxy)phenyl]piperidin-1 -yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide (Q203) or a combination thereof.