NANYANG TECHNOLOGICAL UNIVERSITY;NATIONAL UNIVERSITY OF SINGAPORE
发明人:
Gerhard GRÜBER,Roderick Wayland BATES,Adam HOTRA,Thomas DICK,Kevin PETHE
申请号:
US16485973
公开号:
US20200231550A1
申请日:
2018.02.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to pyrimidine compounds and compositions for treating tuberculosis. These compounds may be used to target the F1 domain of F-ATP synthase and may be used with bedaquiline or 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide (Q203) or a combination thereof.