A natural product energy formulation is provided for a pet, which synergistically aids in (1) function of the heart, (2) energy production, such as in muscles, and/or (3) enhances removal of toxic free radicals. For example, the natural product energy formulation enhances function of the heart, by the use of CoQ10 enables the body to produce more energy through enhanced efficiency of the Krebs cycle, such as by use of L-carnitine and aids in the removal of waste and/or toxins produced in the body, such as by providing anti-oxidants. Hence, the energy formulation synergistically optimizes the heart, muscles, and toxin removal at the same time, which allows for a more active, healthy, and/or interactive pet, where the pet can prolong duration of exercise, increase intensity of exercise, and recover faster. The natural product formulation for pets optionally contains a lipotropic constituent to aid in fat metabolism and/or weight loss.