The invention relates to an antiviral product based on Aframomum Melegueta, which is virolytic, virostatic and water-soluble, for the treatment and prevention of Acquired Immunodeficiency Syndrome (AIDS) and variants thereof.It is produced as follows:The Aframomum Melegueta leaf after collection is dried naturally and reduced to a fine powder.The dried powder is macerated in water sterilized with 100% methanol.The solution is then passed through a filter with a diameter of 0.45 micron and produces a sterilized antiviral, virolytic, virostatic and water-soluble product.The different experiments show that the product:has an antiviral activity,has toxic and destructive effects on cells infected by the AIDS virus,inactivates the virus and appears to be virostatic,is water-soluble,is not complex and has molecules less than 10,000 Da in size and shows resistance to the protease treatment.