The present subject matter relates to devices, systems and methods for the construction of pressure chambers. Such pressure chamber devices, systems, and methods can include a plurality of substantially rigid panels arranged around a space, each of the substantially rigid panels comprising a metal frame formed from a plurality of metal frame elements. One or more connecting plate can be coupled to adjacent pairs of the plurality of substantially rigid panels. In this way, the one or more connecting plate is configured to provide a pressure-tight seal between a respective adjacent pair of the plurality of substantially rigid panels.