Xiaohu FAN,Quichuan ZHUANG,Lei YANG,Pingyan WANG,Qingyan LI
申请号:
US16626721
公开号:
US20200123269A1
申请日:
2018.06.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided is a chimeric antibody immune cell engager comprising a target cell binding domain that specifically binds to an antigen on a target cell, and an immune effector cell binding domain comprising an antigen-binding fragment that specifically binds to an antigen on an immune effector cell. Also provided are pharmaceutical compositions, kits and methods of treatment.