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NAUJIEJI SPIRO[3H-INDOL-3,2' -PIROLIDIN]-2(1H)-ONO JUNGINIAI IR DARINIAI, KAIP MDM2-P53 INHIBITORIAI
专利权人:
Boehringer Ingelheim International GmbH
发明人:
RAMHARTER, Juergen,BROEKER, Joachim,GILLE, Annika,GOLLNER, Andreas,HENRY, Manuel,TOELLE, Nina,WEINSTABL, Harald
申请号:
LT15751029
公开号:
LT3183254T
申请日:
2015.08.20
申请国别(地区):
LT
年份:
2019
代理人:
摘要:
The present invention encompasses compounds of formula (I) wherein the groups R1 to R7, A, V, W, X, Y, n, r and q are as defined herein, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases, and synthetic intermediates.
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