PROBLEM TO BE SOLVED: To advantageously obtain a patch for mucous membranes allowing certainly adhering to and dissolving into the mucous membranes for a moderate time and having good absorptivity of a fentanyl-based compound with a simple production process.SOLUTION: This patch is composed of a (film-shaped) pharmaceutical preparation obtained by including the fentanyl-based compound in a base preparation comprising (A) a semisynthetic water-insoluble high molecular compound, (B) a semisynthetic water-soluble high molecular compound, (C) a synthetic water-soluble high molecular compound, (D) a water-soluble polyhydric alcohol and (E) a pH regulator.COPYRIGHT: (C)2002,JPO【課題】フェンタニル類化合物について、適切な時間確実に粘膜に貼着、溶解すると共に、良好な吸収性を有する粘膜貼付剤を簡単な製造工程で有利に提供する。【要約】(A)半合成水不溶性高分子化合物、(B)半合成水溶性高分子化合物、(C)合成水溶性高分子化合物、(D)水溶性多価アルコール及び(E)pH調整剤とからなる基剤にフェンタニル類化合物を含有せしめることによって、得られる製剤(フィルム状)からなる貼付剤。
