CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE JOSEPH FOURIER (GRENOBLE 1)
发明人:
POLACK, BENOÎT,THOMAS, ALINE
申请号:
EP12712302.4
公开号:
EP2680876B1
申请日:
2012.02.29
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor.