The Asan Foundation;University Of Ulsan Foundation For Industry Cooperation
发明人:
CHANG, Eun-Ju,SONG, Jae-Kwan,KIM, Mi Jeong,CHOI, Bongkun,LEE, Sahmin
申请号：
EP15883426
公开号：
EP3263134A4
申请日:
2015.02.27
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention relates to a composition for preventing or treating valve calcification, containing a dipeptidyl peptidase-4 (DPP-4) inhibitor. The DPP-4 inhibitor according to the present invention may include all of what can inhibit the expression of DPP-4 nucleotides or the activity of DPP-4 proteins, wherein: DPP-4 antibodies, sitagliptin, vildagliptin, saxagliptin, linagliptin, dutogliptin, gemigliptin, alogliptin, Anagliptin, evogliptin, Berberine, Diprotin, or Lupeol； DPP-4 mRNA anti-sense nucleotides, aptamers, small interfering RNA (siRNA), short hairpin RNA (shRNA), and microRNA (miRNA), or RNA interference (RNAi)； or the like can be used.
