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PROCEDES DE PREPARATION D'AG-10, DE SES INTERMEDIAIRES ET DE SELS CORRESPONDANTS
专利权人:
INC.;EIDOS THERAPEUTICS
发明人:
CHAND, POORAN,GUPTA, YOGESH KUMAR,KUMAWAT, RAKESH KUMAR,ALHAMADSHEH, MAMOUN,ZAMBONI, ROBERT
申请号:
CA3051357
公开号:
CA3051357A1
申请日:
2018.02.16
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Provided herein are improved processes for the preparation of a compound of Formula IX (AG- 10). Also provided herein are pharmaceutically acceptable salts of Formula (I) and Formula (lb) as well as crystalline types of Formula IX (AG- 10). The processes described herein provide improved yields and efficiency, while the pharmaceutically acceptable salts and crystalline forms provide unexpected pharmacokinetic properties. Other features and aspects of the present disclosure will be apparent to a person of skill in the art upon reading the remainder of the specification.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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