Morozov, Dmitry Valentinovich,Ulitin, Andrei Borisovich,Zubareva, Ekaterina Sergeevna,Ustiugov, Iakov Iurevich,Karabelskii, Aleksandr Vladimirovich,Korzhavin, Dmitry Valeryevich,Chernovskaya, Tatiana
申请号：
AU2016404449
公开号：
AU2016404449A1
申请日:
2016.12.02
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention relates to the field of biotechnology and proposes monoclonal trispecific binding molecules which specifically bind to human IL-17A, human IL-17F and a human proinflammatory molecule (in particular, TNF-alpha) with a high degree of affinity. The invention also relates to DNA constructs which code for such binding molecules, corresponding expression vectors and production methods, and also treatment methods using said binding molecules.
