MOROZOV, Dmitry Valentinovich,ULITIN, Andrei Borisovich,ZUBAREVA, Ekaterina Sergeevna,USTIUGOV, Iakov Iurevich,KARABELSKII, Aleksandr Vladimirovich,KORZHAVIN, Dmitry Valeryevich,CHERNOVSKAYA, Tatiana
申请号:
EP16900649
公开号:
EP3450456A4
申请日:
2016.12.02
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to the field of biotechnology and provides monoclonal tri-specific binding molecules that specifically bind to human IL-17A, human IL-17F, and a human pro-inflammatory molecule (in particular, TNF±) with high affinity. The invention also relates to DNA constructs encoding said binding molecules, related expression vectors and methods of production, and methods of treatment using said binding molecules.