THE REGENTS OF THE UNIVERSITY OF COLORADO; A BODYCORPORATE
发明人:
HOLERS VERNON MICHAEL,HOLERS Vernon Michael,THURMAN JOSHUA M.,THURMAN Joshua M.,TAUBE CHRISTIAN,TAUBE Christian,GELFAND ERWIN W.,GELFAND Erwin W.,GILKESON GARY STEVEN,GILKESON Gary Steven
申请号:
SI200531781
公开号:
SI1713503T1
申请日:
2005.02.10
申请国别(地区):
SI
年份:
2013
代理人:
摘要:
Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such inhibitors to reduce or prevent airway hyperresponsiveness and/or airway inflammation by selectively inhibiting the alternative complement pathway, thereby treating diseases in which such conditions play a role. Also disclosed is the use of such inhibitors to reduce or prevent other diseases and conditions, including ischemia-reperfusion injury, by inhibition of the alternative complement pathway.